Global Advanced Research Journal of Educational Research and Reviews (GARJERR) ISSN: 2315-5132
February 2017, 6(1): pp. 001-004
Copyright © 2017 Global Advanced Research Journals


Full Length Research Paper

Detection of Blastocystis hominis in patients with neoplasms undergoing chemotherapy or radiation therapy

Boghdady A1, Sabry H2, Nessim NG2, Malek R3, Rizk E1 and Wassef R4  

1Parasitology Department Kasr El-Aini Cairo University.
2Theodor Bilharz Research Institute, Imbaba, Cairo Egypt.
3Clinical Oncology, Department Kasr El-Aini Cairo University.
4National Hepatology and tropical medicine research institute.

Corresponding Author Email:

Accepted 13 January, 2017


This study was performed to estimate the prevalence of Blastocystis hominis in cancer patients undergoing treatment recruited from the Clinical Oncology Department, Cairo University. Two hundred candidates were chosen and divided into four groups. Group A: 50 patients with haematological malignancies treated with chemotherapy. Group B : 50patients with solid organ tumors treated with chemotherapy. Group C: 50 patients with solid organ tumors treated with radiotherapy. Group D: 50 apparently healthy subjects not known to have malignancy but having G I T complaints were included as control group. Stool Samples collected from all groups were subjected to different copro-parasitological methods including, direct stool examination Stool culture and modified Trichrome stain (MTS). In this study, Blastocystis hominis showed to be the most prevalent protozoon in neoplastic patients (26%). Culture on Jone's medium revealed much higher sensitivity in detecting the protozoon (57 cases which constituted 28.5% of the candidates) Again, in this work, infection rates were higher in Group B patients having solid organ tumors and treated with chemotherapy (32%).In this work, it was found that radiation therapy might have caused irreversible damage while chemotherapy probably resulted in reversible cell jeopardy .This study could be of vital importance in endemic areas, where routine survey for parasitic diseases especially opportunistic parasites and protozoa should be done in cancer and immune suppressed patients.

Keywords: Haematological malignancies, solid organ tumors, chemotherapy, radiotherapy, Blastocystis hominis

Related Articles

Ahmed Saad M Alghamdi
Health care outcomes of the various treatment methods of breast cancer in Node-Positive Premenopausal Women with Breast Cancer
Glo. Adv. Res. J. Educ. Res. Rev. June 2016 Vol: 5(6): - [Abstract] [Full Text - PDF] (104 KB)
Original Research Articles
Hisham N Altayb, Mohamed A M Siddig, Nagwa M El Amin, Ahmed Ibrahim Hashim, Maowia M. Mukhtar
Molecular Characterization of CTX-M ESBLs among Pathogenic Enterobacteriaceae isolated from different regions in Sudan
Glo. Adv. Res. J. Educ. Res. Rev. April 2018 Vol: 7(2): - [Abstract] [Full Text - PDF] (1,351 KB)
Yousif M Yousif Abdallah, Mohamed E Gar-elnabi, Abdoelrahman HA Bakary, Alaa MH Eltoum, Abdelazeem KM Ali
Calculation of organs radiation dose in cervical carcinoma external irradiation beam using day’s methods
Glo. Adv. Res. J. Educ. Res. Rev. May 2014 Vol: 3(5): - [Abstract] [Full Text - PDF] (241 KB)
Mohammed A. Ali Omer
Assessment of Day’s Methods for Critical Organs Doses Calculation of Breast Cancer Irradiation Compared with TLD
Glo. Adv. Res. J. Educ. Res. Rev. January 2018 Vol: 7(1): - [Abstract] [Full Text - PDF] (888 KB)
Case Report
Dan Andrei Mitrea, Ana-Maria Vladila, Sanda Maria Nica, Ioan Buraga, Gabriela Mihailescu and Emilia Diaconu
Esthesioneuroblastoma presenting as diplopia and proptosis in a young female patient. Case report and review of the literature
Glo. Adv. Res. J. Educ. Res. Rev. December 2014 Vol: 3(12): - [Abstract] [Full Text - PDF] (715 KB)
Original Research Article
Hind A. A. Al-Zahrani
Solid state fermentation using agro industrial residues for alpha amylase production by an actinomycete isolate from red sea soil
Glo. Adv. Res. J. Educ. Res. Rev. June 2018 Vol: 7(4): - [Abstract] [Full Text - PDF] (458 KB)

Current Issue

Viewing Options

View Full Article - PDF
Download Full Article - PDF

Search for Articles

Boghdady A on Google Scholar
Boghdady A on Pubmed
Sabry H on Google Scholar
Sabry H on Pubmed
Nessim NG on Google Scholar
Nessim NG on Pubmed
Malek R on Google Scholar
Malek R on Pubmed
Rizk E on Google Scholar
Rizk E on Pubmed
Wassef R on Google Scholar
Wassef R on Pubmed


Viewed 1601
Printed 699
Downloaded 1442
Powered By iPortal Works