Global Advanced Research Journal of Microbiology (GARJM) ISSN: 2315-5116
March 2019 Vol. 8(2): pp. 035-037
Copyright © 2019 Global Advanced Research Journals
Major trends in the microbial etiology of urinary tract infection
Ioana Florina Mihai1, Alexandra Georgiana Lacatusu1*, Florina Filip-Ciubotaru1,2, Carmen Dorobat1, C. Romanescu1, Carmen Manciuc1,2
St. Parascheva Infectious Disease Hospital, Iasi
Grigore T. Popa University of Medicine and Pharmacy, Iasi
Accepted 26 March, 2019
Urinary tract infection (UTI) diagnosis is suggested by clinical findings (dysuria, pollakiuria) and confirmed by microbiological analysis of urine. Upon detection of pathogenic agents in the urine, antibiotic susceptibility testing (AST) should precede targeted antibiotic treatment. The growing prevalence of multiple resistant strains is a factor that poses serious challenges to antimicrobial therapy. Purpose: The aim of the study is to evaluate microbial resistance in patients with UTI’s at the St. Parascheva Infectious Disease Hospital in Iasi, Romania. Results: Frequently occurring infectious agents in the lot included gram negative bacteria (GNB), Enterococcus sp. and Candida sp. A percent of 37.8 % of strains were beta-lactamase releasing. The authors also noted increased gram negative bacteria resistance to beta-lactams. Conclusions: The bacteria isolated in decreasing order by frequency were: Escherichia coli, Pseudomonas, Enterococcusand Enterobacter. In order to avoid the occurrence of pan-resistant strains, treatment should be preceded by AST and maintained for an adequate period of time.
Keywords: urinary tract infection, resistance, E. coli, beta-lactams.
Calandra T, Cohen J (2005). International Sepsis Forum Definition of Infection in the ICU Consensus Conference. The international sepsis forum consensus conference on definitions of infection in the intensive care unit. Crit Care Med 2005;33:1538-48
Coman I, Secasan I, Feciche B (2008). Infecţiile tractului urinar. În I. Sinescu, G. Gluck et al, Tratat de Urologie. Ediţia I, Ed. Medicală, Bucureşti, 2008; 875-932.
Naber KG, Schaeffer AJ, Heyns CF (2009). International Consultation on Urogenital Infections, Stockholm, Sweden, March 2009. Urogenital Infections, EAU, edition 2010.
Ronald A (2003). The etiology of urinary tract infection: traditional and emerging pathogens. Dis Mon. 2003; 49: 71-82
Wagenlehner FME, Naber KG (2004). Antibiotics and Resistance of Uropathogens EAU Update Series 2. 2004; 125-135
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