Global Advanced Research Journal of Microbiology (GARJM) ISSN: 2315-5116
April 2019 Vol. 8(3): pp. 051-055
Copyright © 2019 Global Advanced Research Journals

 

Full Length Research Paper

 

Clostridium difficile infection- an overview on recurrences over two years

Alexandra Lacatusu1*, Ioana Iordan1, Carmen Manciuc1,2

1. “ Sf. Parascheva” Infectious Diseases Hospital Iasi, Romania

2. “ Grigore T. Popa ”University of Medicine and Pharmacy Iasi, Romania

Email: alexandra.lacatusu@gmail.com

Accepted 20 April, 2019

 

Abstract

Introduction: Clostridium difficile infection (CDI) is the leading infectious cause of antibiotic-associated diarrhea. The annual rate of the recurrences can be over 100.000 cases and the costs per episode can be over 10.000 euros. Despite the prevention programs implemented in many countries, the rate of the infection continues to increase Purpose: The aim of the study was to evaluate the rate of recurrence of CDI in the patients admitted in “Sf Parascheva” Infectious Diseases Hospital from Iasi, Romania over a period of 2 years (January 1st 2017 to December 31st 2018). Results: Of all the  patients addmited in our hospital for CDI in 2017 and 2018, 30,56% were hospitalized  for the recurrence of the infection.  After analyzing the number of recurrence of the infection  64,89 %  of the patients  were at the first recurrence,  over 19% had a second recurrence of the CDI and the rest, had a 3rd to 6th recurrence. Conclusion: CDI is still a big problem that causes a major burden on the healthcare system and also on the patient. Over 65% of the patients included in the study presented for the first recurrence of CDI, and the rest for second to sixth episode.

Keywords: Clostridium difficile infection, recurrence, treatment.

 

 

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Carmen MD, Mihaela CL, Egidia M, Carmen M, Daniela L, Mihnea H (2012). Boli infecțioase diagnostic și tratament „Gr. T. Popa” UMF Iași 2012

Evans CT, Safdar N (2015). Current trends in the epidemiology and outcomes of Clostridium difficile infection. Clinical Infectious Diseases. 2015;60:S66–S71

Ioana FI, Anca MA, Irina AS, Nastase E, Florina Filip-Ciubotaru, Carmen Manciuc (2017). Increasing incidence of recurrent Clostridium difficile infection Vol 121 No 3 (2017): The Medical-Surgical Journal

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