Global Advanced Research Journal of Microbiology (GARJM) ISSN: 2315-5116
May 2018 Vol. 7(3): pp. 048-056
Copyright © 2018 Global Advanced Research Journals


Full Length Research Paper


Acinetobacter baumannii complex and its antibiotics susceptibility in selected hospital's intensive care units at Sana’a city-Yemen

Abdulrahman Ali Mohammed Zabada*, Sultan Ayesh Mohammed Saghirb, Anwar Kassem Al-Madhagic, Khaled Abdulkarim Al-Moyedc


aDepartment of Medical Microbiology, High Institute for Health Sciences, Sana`a, Yemen

bDepartment of Medical Analysis, Princess Aisha Bint Al-Hussein College of Nursing and Medical Sciences, Al-Hussein Bin Talal University, Ma`an, Jordan.

cDepartment of Medical Microbiology, Faculty of Medicine and Health Sciences, Sana`a University, Yemen



Accepted 06 April, 2018



Background and Aim: The main challenge with Acinetobacter baumannii complex (Abc) is its ability to rapidly cause antimicrobial-resistance and ineffective antibiotic therapy. This study is therefore designed to investigate the prevalence rates, infection risk factors and antibiotic susceptibility patterns of Abc in ICUs. Methods: This Cross-Sectional study was carried out for duration of one year in the intensive care units (ICU) units of three hospitals in Sana`a city, Yemen with 280 ICU patients as participants and 80 environmental samples. Results: The prevalence rate of Abc of 7.1% was determined for 280 individual patients admitted in ICU, with 12.9 % in respiratory specimens and 1.4% in blood specimens. All isolated Abc`s became multi-drug resistant over time. Resistance rates were found to be 95% for Piperacillin-Tazobactam, 90% for Imipenem, Cefepime and Ticracillin, 80 % for Amikacin and Doxcycyclin, and 60% for Levofloxacin. However, no resistant isolates were found for Colistin and polymyxin B. The prevalence of Abc in ICUs environment was 8.8% and these isolates were indistinguishable from the clinical isolates using biotyping and antibiotics susceptibilities.  Conclusions: Based on its characteristic multi-drug resistance and potential risk to ICU patients, suggestions were offered to prevent nosocomial infections by Abc.   

Keywords:  Acinetobacter baumannii, Intensive Care Units, antibiotics susceptibility, Yemen.





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