Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
January 2013 Vol. 2(1), pp. 006-012
Copyright © 2013 Global Advanced Research Journals

 

Full Length Research Paper

The Sero-prevalence of Hepatitis B surface antigen and anti-hepatitis C antibody among women attending antenatal clinic at a tertiary health facility in the Niger Delta of Nigeria

Kemebradikumo Pondei1* and Isa Ibrahim2

1Department of Medical Microbiology, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University, Amassoma, Wilberforce Island, Bayelsa State, Nigeria.
2Department of Obstetrics and Gynaecology, Faculty of Clinical Sciences, College of Health Sciences, Niger Delta University, Amassoma, Wilberforce Island, Bayelsa State, Nigeria.

*Corresponding author E-mail: kemepondei@hotmail.com; Tel: +2348030940882

Accepted 28 January, 2013

Abstract

Asymptomatic Hepatitis B and C infections are common and when occuring in pregnancy can be transmitted to the newborn. To determine the sero-prevalence rates of asymptomatic Hepatitis B and C infections among pregnant women. 300 pregnant women attending antenatal clinic were consecutively recruited for study. Demographic and past clinical histories were obtained using a questionnaire. Serum samples from each study subject were tested using third-generation enzyme immunoassay kits for Hepatitis B surface antigen (HBsAg) and antibodies against Hepatitis C. Hepatitis B surface antigen prevalence was 3.67% (95% CI: 1.55 - 5.79) whilst anti-Hepatitis C antibody prevalence was 1.33% (95% CI: 0.04 - 2.62). 80% of the subjects with either Hepatitis B or C infections (12 out of 15) had traditional scarification marks on their bodies, 66.7% had undergone at least one previous termination of pregnancy, 26.7% had tattoos, 6.67% had previous blood transfusions, and 26.7% had undergone at least one surgical operation. However, none of the suspected risk factors had a significant relationship with hepatitis infection. Asymptomatic Hepatitis B and C infections are present in pregnant women. Routine screening of pregnant women for HBV and HCV should be instituted in order to detect infection early and prevent or reduce vertical or perinatal transmission.

Keywords: Hepatitis, pregnancy, risk factor, ante-natal screening

 

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