Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
January 2016 Issue Vol. 5(1), pp. 035-041
Copyright © 2016 Global Advanced Research Journals

 

Full Length Research Paper

Assessment of Bone Mineral Density and Functional status in Children with Hemophilic Arthropathy

Rasha Samir Abd EL Naeem1, Hanan EL Sebaie El Hefnawy1, Ola Abd EL NaserAbd EL Aziz1, Dalia Mohamed Ezz EL Din El Mikkawy1*, Azza Abdel GawadTantawy2 and Shereen Mohamed Abd El-Ghany2.

1Department of Physical Medicine,Rheumatology and Rehabilitation, Ain Shams University Hospitals, Faculty of Medicine, Ain Shams University.
2Department of Pediatrics, Ain Shams University Hospitals, Faculty of Medicine, Ain Shams University.

*Corresponding Author E-mail: drdaliaezz74@yahoo.com

Accepted 09 February, 2016

Abstract

Haemophilia and osteoporosis accompanied by chronic pain, loss of independence and increased mortality. Functional Independence Score in Hemophilia (FISH) has been developed as a measure of disability in hemophilic patients. To assess bone mineral density, and functional status in children with hemophilic arthropathy and study possible relation to articular affection. This study included twenty haemophilic male patients, assessed for body mass index, hemophilia joint health score (HJHS), functional independence score in hemophilia (FISH), and bone mineral density (BMD). 8 patients (40%) hadlow BMD, 12 patients (60%) had average BMD. A highly significant negative correlation between HJHS total and DXA were found, while a highly significant positive correlation between total functional score and DXA. A significant negative correlation between number of attacks and DXA. A positive significant correlation between age, degree of factor deficiency and number of attacks with HJHS score, while a negative significant correlation was detected of total function score and HJHS. A highly significant negative correlation between each of number of attacks and degree of factor deficiency with total functional score. A highly significant relation between degree of deficiency and a significant correlation between type of treatment and total functional score. Bone mineral density positively correlated with functional score and negatively correlated with HJHS score total and number of attacks of bleeding, which is the main contributor to arthropathy and reduced bone mass in the hemophiliacs. Decrease in total functional score affected mainly by increase in HJHS.

Keywords: Haemophilic arthropathy, Functional status, Bone density.

 

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Rasha Samir Abd EL-Naeem on Google Scholar
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Hanan EL Sebaie El-Hefnawy on Google Scholar
Hanan EL Sebaie El-Hefnawy on Pubmed
Ola Abd EL NaserAbd EL-Aziz on Google Scholar
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