Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
January 2018 Issue Vol. 7(1), pp. 028-033
Copyright © 2018 Global Advanced Research Journals

 

Full Length Research Paper

Assessment of Endemic Goitre of Children in Eastern Sudan (Red Sea State) Using Ultrasonography and ELISA

Shazaly Khojaly1,4, Mohamed Yousef1,2, Mohammed Garelnabi1, Mogahid M.A Zidan3, 4*, Auis Bashir1, Mahmoud S Babiker5, Eltag M.I. Madwi6 and Abbas Khalid Abbas Ibrahim3, 4

1Diagnostic radiologic department College of Medical Radiologic science, Sudan University of Science and Technology, Khartoum, Sudan
2Radiological Science Program, Batterjee Medical College for Science and Technology, Jeddah, KSA
3Radiological Science and Nuclear Medicine College, The National Ribat University, Khartoum, Sudan
4Medical Imaging Technology Department, Al-Ghad International College of Applied Medical Science, Abha, KSA
5Taibah University, Faculty of Applied Medical Sciences, Department of diagnostic radiologic technology, AL Madinah, KSA.
6Department of Diagnostic Radiology, Rashid Hospital, Dubai Health Authority, UAE.

*Corresponding Author  E-mail: jojo.zidan999@gmail.com, mozidan@gc.edu.sa; Mobile: +966-506270174 

Accepted 18 December, 2017

Abstract

The thyroid gland is a butterfly-shaped organ located at the base of your neck. It releases hormones that control metabolism—the way your body uses energy. The thyroid gland has an essential role in regulating vital body functions. This study aimed to assess an endemic goiter in school-aged children in Eastern Sudan (Red Sea State) and to estimate the measurement of standard thyroid gland dimensions and thyroid hormones level Using Ultrasonography and ELISA Technique. A total of 100 children (50 males, 50 females) with mean age of 10.96 ±3.4. Ranged from (6-18) year old., this study was conducted done  in the period from May 2017 to August 2017, All the participants undergone thyroid ultrasound and thyroid hormone level test, subjects with history of goiter  thyroid disease were excluded from the study, thyroid measurements (length, width, and depth) were used to estimate thyroid volume using ellipsoid formula. Thyroid hormones (TSH, T3, and T4)  were estimated using Toso full automation. The study revealed that  subjects of the study (17%) of the participants had goiter, four female (4%) and 13 males (13%) with age ranged (6-11 years) with an increase in TSH and T3  and decreased in T4 level. The mean of thyroid volume for normal participants was 5.03± 0.92 mL and for those who had goiter was 5.72 ± 1.77mL.TSH, T3, T4 for normal participants and for those with goiter were (1.83 ± 0.81, 1.4 ± 0.58 UIu/nL), (3.56 ± 0.34, 4.07 ± 0.58 Pg/Nl) and (1.19 ± 0.15, 1.68 ± 0.72 ng/DI) respectively. It concluded that there were positive correlations between the age and the thyroid volume, it increases with the age increase, the Rt. lobe  was more large than the Lt. lobe, the thyroid volume higher in male than female, and this study found the TSH, T3 and T4 decreases with ages in normal  and goiter subject

Keywords: Thyroid gland, TSH, Goiter, Hormone Level

 

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