Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
October 2014 Vol. 3(10), pp. 275-280
Copyright © 2014 Global Advanced Research Journals


Case Report

A Rare Case of Classic Homocystinuria with Hyperpigmentation

Haydar A. Abdelrazig1*, Dina  A.  Hassan2, Suad Y. Alkarib3 and Mohamed A. Mahgoub4

1Cosultant Paediatrician, MD, Department of Paediatrics, Omdurman Military Hospital, Khartoum, Sudan.
2Consultant Biochemist, PhD, Department of Biochemistry Faculty of Medicine, Karary University, Khartoum, Sudan.
3Consultant Pharmacist, PhD, Dean of Faculty of Pharmacy, Karary University, Khartoum, Sudan.
4Consultant Haematologist, MD, Department of Haematology, Central Laboratory, Omdurman Military Hospital, Khartoum, Sudan.

*Corresponding Author E-mail:; Phone: 00249-123431031; Fax:  00249-186551513  

Accepted 20 October, 2014


An eleven years old girl was admitted to paediatric ward, at Omdurman Military Hospital, Khartoum, Sudan, with generalized skin hyperpigmentation, mental retardation and ectopia lentis. She was diagnosed as a case of classic homocystinuria  (type I) with megaloblastic anaemia. Vitamin B12 and folicacid levels should be monitored  periodically,  in patients with classic homocystinuria.

Keywords: Homocystinuria, Hyperpigmentation, Megaloblastic anemia, Vitamin B12, Folic acid.

Related Articles

Original Research Articles
Soheir Mahmoud, Maisa Shalaby, Hoda Sabry, Neimat Amer, Nevine Guirguis ,Wafaa El Komy Mennat Al-Rahman, and Mona Magdy
Additive Effect of Some Elements to vitamin B17 Administration in Immunosuppressed Mice Infected with Cryptosporidium
Glo. Adv. Res. J. Med. Med. Sci. November 2019 Vol: 8(1): - [Abstract] [Full Text - PDF] (1,228 KB)
A.A. Kandil, A.E. Sharief and Marwa H.S. Ahmed
Effect of Antioxidant and Growth Hormones on Seedling Parameters of New and Aging Seed of Some Maize Hybrids
Glo. Adv. Res. J. Med. Med. Sci. March 2019 Vol: 8(3): - [Abstract] [Full Text - PDF] (1,129 KB)
Muhammad Imran Qadir, Sidra Zafar
Upshot of Blood Group with handedness
Glo. Adv. Res. J. Med. Med. Sci. April 2019 Vol: 8(3): - [Abstract] [Full Text - PDF] (96 KB)
Kandil A.A., A.E. Sharief and Marwa S. Ahmed
Seed Germination Characters of New and Aging Seed of Some Maize Hybrids as Influenced by Antioxidant and Growth Hormones
Glo. Adv. Res. J. Med. Med. Sci. March 2019 Vol: 8(3): - [Abstract] [Full Text - PDF] (1,683 KB)
Hussein HK, Elnaggar MH and Al-Zahrani NK
Antioxidant role of folic acid against reproductive toxicity of cyhalothrin in male mice
Glo. Adv. Res. J. Med. Med. Sci. July 2012 Vol: 1(4): - [Abstract] [Full Text - PDF] (714 KB)

Current Issue

Viewing Options

View Full Article - PDF
Download Full Article - PDF

Search for Articles

Haydar A Abdelrazig on Google Scholar
Haydar A Abdelrazig on Pubmed
Dina A Hassan on Google Scholar
Dina A Hassan on Pubmed
Suad Y Alkarib on Google Scholar
Suad Y Alkarib on Pubmed
Mohamed A Mahgoub on Google Scholar
Mohamed A Mahgoub on Pubmed


Viewed 2248
Printed 669
Downloaded 1774
Powered By iPortal Works