Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
October 2015 Vol. 4(10), pp. 435-440
Copyright © 2015 Global Advanced Research Journals

 

Full Length Research Paper

Study of Increased Atherosclerosis Risk In Hepatitis C virus and Cytomegalovirus Seropositive Haemodialysis Patients

Ghada Al-Ghazaly1* and Tarek El-Sharawy2

1Lecturer, Internal Medicine Department, Faculty of medicine, Tanta University, Egypt.
2Assistant Professor, Internal Medicine Department, Faculty of medicine, Tanta University, Egypt.

*Corresponding  Author  E-mail: dodoya288@yahoo.com

Accepted 02 October 2015

Abstract

Hepatitis C virus (HCV) is the most common liver disease in renal dialysis patients. Also, cytomegalovirus (CMV) is a common infection in chronic hemodialysis patients (CHD).  HCV and CMV patients are more likely to have carotid atherosclerosis plaques as compared to negative individuals. The aim of this study is to assess the association between HCV and CMV seropositivity, dyslipidemia, carotid artery plaques and media intima thickening in hemodialysis patients. Sixty patients with chronic kidney disease (CKD) on regular hemodialysis were selected from hemodialysis unit in Tanta university hospital.  All subjects were subjected to medical history taking, physical examination, complete blood picture (CBC), fasting blood glucose (FBS), liver function tests, lipid profile, serum calcium, serum phosphorus, INR, prothrombin concentration , C-reactive protein (CRP), HCV Ab (ELISA) and CMV IgG and Duplex on both Carotid arteries with measurement of intimal medial thickness. The prevalence of atherosclerosis in HCV, CMV positive and negative patients undergoing hemodialysis is not influenced by many factors (p value >0.05): sex, age, and body mass index, systolic and diastolic blood pressure, Also there was no significant change in serum albumin, bilirubin, prothrombin concentration, INR, CBC, FBS, CRP, serum phosphorus and ionized calcium. There was significant increase in atherosclerosis among HCV and CMV positive compared to negative patients undergoing hemodialysis as proved by Carotid Duplex. Atherosclerosis is increased in HCV and CMV seropositive compared to seronegative patients under hemodialysis as proved by Carotid Duplex.

Keywords: Hepatitis C virus, cytomegalovirus, Haemodialysis, Atherosclerosis, Carotid Duplex, Risk factors

Related Articles


Original Research Articles
Bello, S. I.
Adherence and generic substitution among hypertensive patients in a specialist hospital
Glo. Adv. Res. J. Med. Med. Sci. February 2012 Vol: 1(1): - [Abstract] [Full Text - PDF] (118 KB)
El-Kersh TA, Marie MA, Al-Sheikh YA and Al-Kahtani SA
Prevalence and risk factors of community-acquired urinary tract infections due to ESBL-producing Gram negative bacteria in an Armed Forces Hospital in Sothern Saudi Arabia
Glo. Adv. Res. J. Med. Med. Sci. August 2015 Vol: 4(8): - [Abstract] [Full Text - PDF] (374 KB)
Saleh A S AL-Abdulhadi
Spotlight into some Abnormalities of Human Chromosome in Saudi Arabia
Glo. Adv. Res. J. Med. Med. Sci. January 2018 Vol: 7(1): - [Abstract] [Full Text - PDF] (257 KB)
Hayfaa A Wahabi
Outcome of Trial of Labour after Caesarean Section at King Khalid University Hospital
Glo. Adv. Res. J. Med. Med. Sci. November 2016 Vol: 5(11): - [Abstract] [Full Text - PDF] (98 KB)
Lawrence Ehis Okoror, and Samuel Ayodeji Osanyinlusi
Prevalence, Risk and High Human Papilloma Virus IgM and IgG Concentration in Human Immune Deficiency positive individuals in Southwest Nigeria
Glo. Adv. Res. J. Med. Med. Sci. November 2017 Vol: 6(7): - [Abstract] [Full Text - PDF] (323 KB)
Damulak Obadiah Dapus, Piwuna TO, Joseph DE, Ogbenna AA, Kut SD, Godit P, Bodunde T and Chetle LD
Hepatitis C Virus Antibody Among Blood Donors: The Experience in a Nigerian Blood Transfusion Service Centre
Glo. Adv. Res. J. Med. Med. Sci. May 2013 Vol: 2(5): - [Abstract] [Full Text - PDF] (159 KB)

Current Issue

Viewing Options

View Full Article - PDF
Download Full Article - PDF

Search for Articles

Ghada Al-Ghazaly on Google Scholar
Ghada Al-Ghazaly on Pubmed
Tarek El-Sharawy on Google Scholar
Tarek El-Sharawy on Pubmed

Statistics

Viewed 3865
Printed 744
Downloaded 2009
Powered By iPortal Works