Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
October 2017 Vol. 6(10), pp. 240-244
Copyright © 2017 Global Advanced Research Journals

 

Full Length Research Paper 

Antibacterial activity of crude herbal extracts of Zingiber officinale and Curcuma longa against 13 reference bacterial species

Sami S. Ashgar

Microbiology Department, College of Medicine, Umm Al-Qura University, Saudi Arabia.

E-mail: ssashgar70@hotmail.com; Mobile: +966(0) 505 794 955

Accepted 09 October, 2017 

Abstract

Medicinal plants acquired great attention for their miracle properties against various human illnesses. In this laboratory-based study, Antibacterial effectiveness of Curcuma longa and Zingiber officinale (Ginger) were extracted in aqueous, 70% ethanol and ethyl acetate solvents and investigated against 13 various American type culture collection (ATCC( strains  by the mean of determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Results demonstrated that ethyl acetate extract of Curcuma longa was superior to other solvents versus Enterococcus faecalis, Enterococcus faecalis (VRE), Staphylococcus aureus (MRSA) and Staphylococcus epidermidis with inhibition zones range (12-19mm) and exhibited killing concentration varies between 25-50 mg/ml. Acinetobacter baumannii expressed visible sensitivity to Curcuma longa extracted in aqueous, ethanol and ethyl acetate solvents. Bactericidal activity was experimentally constant at a concentration of 50mg/ml. Ethyl acetate extract of Ginger, on the other hand, was the only extract that showed antibacterial activity against three reference bacterial strains include E. faecalis, S. aureus and Staphylococcus aureus (MRSA), with inhibition zones range (12-19mm) and MBC value of 100, 12.5 and 25 mg/ml, respectively. In conclusion, demonstrated antibacterial activity of Curcuma longa and Zingiber officinale can be further invested as potential natural antibiotics against some multi-resistant pathogens. 

Keywords: Curcuma longa, Zingiber officinale, MIC, MBC, ethyl acetate, ethanol, aqueous, ATCC strains.

 

References

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