Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
October 2017 Vol. 6(10), pp. 267-270
Copyright © 2017 Global Advanced Research Journals


Case Report 

Copper nanoparticles as treatment of diabetic foot ulcers: A case report

T. Lopez Goerne1,2*, A. Arévalo3, P. Ramírez1 and P. Larraza1.

1Laboratorio de Nanotecnología y Nanomedicina, Departamento de Atención a la Salud. Universidad Autónoma Metropolitana-Xochimilco. Calzada del Hueso 1100, Col. Villa Quietud, Delegación Coyoacán, C. P. 04960, Ciudad de México.
2Facultad de Medicina, Universidad Nacional Autónoma de México.
3Laboratorios de Nanomedicina y Nanotecnología. Nano Tutt S.A. de C.V.

*Corresponding Author E-mail:

Accepted 27 October, 2017


Copper nanoparticles were prepared by the sol-gel process to obtain nanoparticles of 2.4 nm. The material was characterized by Transmission Electron Microscopy (TEM) and Fourier Transformed Infrared Spectroscopy (FTIR). This nanomaterial was used to treat a diabetic foot ulcer in a 58 years old male patient. The patient presented type 2 diabetes mellitus with13 years of evolution, with macro and micro vascular complications. The illness shown by retinopathy, state 2 chronic renal disease, peripheral artery disease, critical limb ischemia with the presence of an ulcer in the right heel and anipsilateral necrotic lesion in the 2nd, 3rd, and 4th toes. This patient was already programmed for a supracondylar amputation. In order to avoid the amputation, the patient was included into the clinic trial to be treated with copper nanoparticles. After a three-month treatment, the ulcer evolved with positive clinical results.

Keywords: Nanoparticles, copper, diabetic foot, ulcers, diabetes, case report



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