Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
December 2012 Special Anniversary Review Issue Vol. 1(11), pp. 312-319
Copyright © 2012 Global Advanced Research Journals


Full Length Research Paper

Sleep heart rate circadian rhythm variability in temporal lobe epileptic Egyptian children

Mohammed Al-Biltagi1*, Osama Abd Rab Elrasoul Tolba1, Tarek mohamed Elgohary1, Osama Abo Elmagd Elkholy2 and Rasha Abdelgelil Abdelwanis1

1Pediatric Department, Faculty of Medicine, Tanta University, Tanta, Gharbia Governate, Egypt.
2Neuropsychiatry, Faculty of medicine, Alexandria University Egypt.

*Corresponding Author: Email:; Tel: +20102209797 /+973-39545472/ Fax: +973-17-590495

Accepted 03 December, 2012


The aim of this study was to measure interictal circadian rhythm variability of heart rate (HR) in Egyptian children with temporal lobe epilepsy (TLE) using a 24 hours ECG recording. A group of 40 children suffering from partial epilepsy subdivided into group A with 21 children who had controlled temporal lobe epilepsy and group B with 20 children suffered uncontrolled temporal lobe epilepsy. A third group of 40 healthy children was studied as a control group. An ambulatory two channel-5-lead electrocardiography (ECG) recording was performed in both epileptic children and the controls. A computer assisted analysis of heart rhythm and heart rate variability recorded over a 24 hours period of normal daily activity of the children was done. There was lower heart rate variability (HRV) in temporal lobe epileptic children than in normal controls. Also the HRV was lower in children with uncontrolled TLE than in children with controlled TLE. There was a disturbance of the autonomic nervous system (ANS) function in epileptic children with reduction of the vagal tone compared to normal children as indicated by the differences in HRV which suggests that the parasympathetic component of the ANS is strongly implicated in the pathogenesis of epilepsy.

Keywords: Egyptian Children; Heart Rate Variability; Sleep Circadian Rhythm; Temporal Lobe Epilepsy.


Current Issue

Viewing Options

View Full Article - PDF
Download Full Article - PDF

Search for Articles

Mohammed Al-Biltagi on Google Scholar
Mohammed Al-Biltagi on Pubmed
Osama Abd Rab Elrasoul Tolba on Google Scholar
Osama Abd Rab Elrasoul Tolba on Pubmed
Tarek mohamed Elgohary on Google Scholar
Tarek mohamed Elgohary on Pubmed
Osama Abo Elmagd Elkholy on Google Scholar
Osama Abo Elmagd Elkholy on Pubmed
Rasha Abdelgelil Abdelwanis on Google Scholar
Rasha Abdelgelil Abdelwanis on Pubmed


Viewed 1646
Printed 776
Downloaded 792
Powered By iPortal Works