Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
December 2016 Special Issue Vol. 5(12), pp. 283-286
Copyright © 2016 Global Advanced Research Journals

 

Case Report 

Spinal Nephroblastoma in a Dog

Sevil Atalay Vural1*, Tuncer Kutlu1, Omer Besalti2 and Pinar Can2

1Ankara University, Faculty of Veterinary Medicine, Department of Pathology, 06110, Diskapi-Ankara, Turkey
2Ankara University, Faculty of Veterinary Medicine, Department of Surgery, 06110, Diskapi-Ankara, Turkey

*Corresponding Author E-mail: sevilvural@yahoo.com; Phone:  +90 312 3170315 - 4276; Fax:  +90 312 3164472

Accepted 13 December, 2016

Abstract

The objective of this study is to report Magnetic Resonance Imaging (MRI), histological and immunohistochemical findings of spinal  nephroblastoma in a 2-year-old mixed breed dog.  There was a mass located at the level of thoracal 12–13 and it was hypo intense in T2 w images and iso/hypo intense in T1 w images, and syringohydromyelia was also accompanying in both cranially and caudally. Macroscopically, the mass was 4 mm in diameter, grey color and well demarcated. Histologically, it was composed of cuboidal to ovoid cells with indistinct borders and a scant to midly amphophilic, generally hyperchromatic nuclei. Tumor cells formed tubules, ribbons and glomeruloid structures within fibrovascular background. Immunohistochemically, neoplastic cells especially in tubules and glomeruloid structures stained pan cytokeratin. On the other hand, fibrovascular stroma and capsule were stained  α –smooth muscle actin (α – SMA) and vimentin sera.

Keywords: Dog, nephroblastoma, spinal cord


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