Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
December 2017 Special Issue Vol. 6(12), pp. 316-319
Copyright © 2017 Global Advanced Research Journals


Short Communication

Development and Clinical Evaluation of Rapid Diagnostic Kit for Hemorrhagic Fever with Renal Syndrome

Dong-Hoon Shin1, Sungman Park2, Young-Jin Kim2, Sora Kim3, Min Soo Kim2, Soo-Dong Woo4 and Yoon-Won Kim5*

1Department of Laboratory Medicine, College of Medicine, Hallym University, Chuncheon, Republic of Korea
2Institute of Medical Science, School of Medicine, Hallym University, Chuncheon, Republic of Korea
3Industry-Academic Cooperation Foundation, Hallym University, Chuncheon, Republic of Korea
4Department of Agricultural Biology, College of Agriculture, Life and Environment Science, Chungbuk National University, Cheongju, Republic of Korea
5Department of Microbiology, College of Medicine, Hallym University, Chuncheon, Republic of Korea

*Corresponding  Author  E-mail:; Tel.: +82 33 248 2633; Fax: +82 33 241 1664

Accepted 21 December, 2017 


Hemorrhagic fever with renal syndrome (HFRS) is one of the acute febrile illnesses. This study has analysed ‘Immune Med Hanta Rapid Kit’, a medical device for in vitro diagnosis of HFRS using immunochromatographic assay. This kit was evaluated by the test of the IgM and IgG to the Hantavirus. In a clinical evaluation with 194 specimens (91 HFRS, 48 other infectious diseases, and 55 healthy controls), the kit was shown 96.7 % sensitivity and 97.1 % specificity. These results demonstrate that this kit is the potentially useful diagnostic device which can perform a rapid, accurate, and simple diagnosis of HRFS clinically.

Keywords: Rapid Diagnostic Kit, Immunochromatographic assay, HFRS, Nucleocapsid protein, Baculovirus expression



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