Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
February 2016 Issue Vol. 5(2), pp. 053-066
Copyright © 2016 Global Advanced Research Journals


Full Length Research Paper

Impact of chronic liver disease on HRQOL and its association with anaemia in Al-Gharbiyah Governorate, Egypt

Alghazaly, G*,  Abd El Raouf, Y. M and Zaglol kh

Internal Medicine Department, Faculty of Medicine, Tanta University, Egypt.

*Corresponding Author E-mail:

Accepted 14 February, 2016


There has been a rapid development in the concept of HRQOL due to growing awareness of the importance of understanding the effect of health related intervention on patients’ routine life, rather than only on treatment of their bodies. Because this concept is important for those who live with less optimism of cure such as decompensated liver cirrhosis patients therefore HRQOL is important in terms of physical and psychosocial wellbeing for patients; suffering from chronic debilitating illnesses. We evaluated the impact of chronic liver disease on HRQOL, looked for differences in HRQOL by type and severity of disease, and tried to identify the association of HRQOL with anemia. This study was conducted on 250 patients with chronic liver disease recruited from the hepatology outpatient clinic of Clinical Hepatology Department, El-Mahallah Hepatology Teaching Hospital and hepatology outpatient clinic of Internal Medicine Department, Tanta University Hospitals. Health related quality of life (HRQOL) had been assessed by using chronic liver disease questionnaire (CLDQ). The relationship between severity of impairment of quality of life and hemoglobin level was found statistically significant. The differences in severity of impairment of activities in relation to hemoglobin level were found statistically not significant. The relationship between hemoglobin level and emotional function was found statistically significant. The worries domain in relation to hemoglobin level was not significant. The total score of quality of life shows a negative significant correlation with hemoglobin level where the correlation coefficient was -0.195(p=0.002).

Keywords: Chronic liver disease, anemia and health related quality of life (HRQOL)


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