Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
March 2016 Issue Vol. 5(3), pp. 074-081
Copyright © 2016 Global Advanced Research Journals


Full Length Research Paper

Cytotoxicity and Bioactive Compounds from Diethyl Ether Extract of lotus halophilus Boiss Et Spruner Growing in Egypt

Amani M. D. El-Mesallamy1, Shalabia S. Emam2, Mohamed H. M. Abed El-Azim1* and Ibrahim M. Sanad2

1Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt
2Aromatic and Medicinal Plants Department, Desert Research Center, Cairo, Egypt

*Corresponding  Author  E-mail:

Accepted 11 March, 2016


In the present study we carried out the GC-MS of lipid diethyl ether extract of the Lotus halophilus boiss et spruner aerial parts to identify its chemical compositions. Fatty acids of the saponifiable fraction revealed the presence of twelve saturated fatty acids and eleven unsaturated fatty acids, in addition a series of (C4-C69) hydrocarbons and three sterols were identified in the unsaponifiable fraction. Cytotoxic and antioxidant activities were carried out for the ether extract of the plant. The ether extract showed cytotoxic activity against HEPG2 and MCF7, while it was unable to inhibit the growth of HCT; also it showed significant antioxidant activity.   

Keywords: Lotus halophilus, GC-MS, fatty acids, hydrocarbons, sterols, cytotoxic andanti-oxidant activities.

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Amani MD El-Mesallamy on Google Scholar
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Shalabia S Emam on Google Scholar
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Mohamed HM Abed El-Azim on Google Scholar
Mohamed HM Abed El-Azim on Pubmed
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