Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
March 2016 Issue Vol. 5(3), pp. 074-081
Copyright © 2016 Global Advanced Research Journals

 

Full Length Research Paper

Cytotoxicity and Bioactive Compounds from Diethyl Ether Extract of lotus halophilus Boiss Et Spruner Growing in Egypt

Amani M. D. El-Mesallamy1, Shalabia S. Emam2, Mohamed H. M. Abed El-Azim1* and Ibrahim M. Sanad2

1Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt
2Aromatic and Medicinal Plants Department, Desert Research Center, Cairo, Egypt

*Corresponding  Author  E-mail: drmhm1982@gmail.com

Accepted 11 March, 2016

Abstract

In the present study we carried out the GC-MS of lipid diethyl ether extract of the Lotus halophilus boiss et spruner aerial parts to identify its chemical compositions. Fatty acids of the saponifiable fraction revealed the presence of twelve saturated fatty acids and eleven unsaturated fatty acids, in addition a series of (C4-C69) hydrocarbons and three sterols were identified in the unsaponifiable fraction. Cytotoxic and antioxidant activities were carried out for the ether extract of the plant. The ether extract showed cytotoxic activity against HEPG2 and MCF7, while it was unable to inhibit the growth of HCT; also it showed significant antioxidant activity.   

Keywords: Lotus halophilus, GC-MS, fatty acids, hydrocarbons, sterols, cytotoxic andanti-oxidant activities.

Related Articles


Original Research Articles
Magdy A Abu-Gharbia, El-Sayed M Soltan, Osman M El-Maghraby and Walaa M Abd El-Raheem
Antibacterial effect of some Egyptian plants on antibiotic-resistant oral bacteria
Glo. Adv. Res. J. Med. Med. Sci. January 2015 Vol: 4(1): - [Abstract] [Full Text - PDF] (121 KB)
Imeh J Okop, Fiokedu S Okorie and Clement O Obadimu
Quantitative evaluation of the spatial distribution and penetration of liquid hydrocarbons in petroleum spilled soil
Glo. Adv. Res. J. Med. Med. Sci. September 2012 Vol: 1(6): - [Abstract] [Full Text - PDF] (1,307 KB)
Magdy A Abu-Gharbia, Michael N Agban, El-Mewafy A El-Ghadban and Rasha Z Abdelmasieh
Antibacterial activity of Cymbopogon citratus and Rosmarinus officinalis essential oil against carbapenems resistant Klebsiella pneumonia strains (as nosocomial pathogen) isolated from intensive care units of two hospitals
Glo. Adv. Res. J. Med. Med. Sci. January 2015 Vol: 4(1): - [Abstract] [Full Text - PDF] (94 KB)
S Ünlü, E Sarı, R Apak, N Balcı and B Koldemir
Distribution and source identification of polycyclic aromatic hydrocarbons in sediments of the Ambarlı Port area, Sea of Marmara, Turkey
Glo. Adv. Res. J. Med. Med. Sci. August 2013 Vol: 2(6): - [Abstract] [Full Text - PDF] (999 KB)
Peter R Berti, Elena Villacrés, Gabriela Segovia, Nelson Mazon, Eduardo Peralta.
Lupinus mutabilis Sweet, a traditional Ecuadorian grain: Fatty acid composition, use in the Ecuadorian food system, and potential for reducing malnutrition.
Glo. Adv. Res. J. Med. Med. Sci. June 2013 Vol: 2(6): - [Abstract] [Full Text - PDF] (230 KB)
Hernández, M. A, Hernández R.P, Espinosa R.R, Guillen D.S, Cianna, M.I.
Scientific Communication Allelopathic influence of Ipomoea batatas (L.) Lam. commercial clone 'CEMSA 78-354' on weeds
Glo. Adv. Res. J. Med. Med. Sci. October 2015 Vol: 4(10): - [Abstract] [Full Text - PDF] (395 KB)

Current Issue

Viewing Options

View Full Article - PDF
Download Full Article - PDF

Search for Articles

Amani MD El-Mesallamy on Google Scholar
Amani MD El-Mesallamy on Pubmed
Shalabia S Emam on Google Scholar
Shalabia S Emam on Pubmed
Mohamed HM Abed El-Azim on Google Scholar
Mohamed HM Abed El-Azim on Pubmed
Ibrahim M Sanad on Google Scholar
Ibrahim M Sanad on Pubmed

Statistics

Viewed 1972
Printed 368
Downloaded 1508
Powered By iPortal Works