Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
April 2015 Vol. 4(4), pp. 190-193
Copyright © 2015 Global Advanced Research Journals


Full Length Research Paper

In vitro antibacterial activity of Ipomoea reptans extracts

Mahmoud H Gad1, Rehab M Mohamed3, Nagwa M El-Sawi2*, Sabry H Younes2 and El-Mewafy A El-Ghadban1

1Department of Medicinal and Aromatic Plants Research, Horticulture Research Institute, Agriculture Research Center, Dokki, Giza, Egypt.
2Department of Chemistry, Faculty of Science, Sohag University, Sohag, Egypt.
3Department of Botany, Faculty of Science, Sohag University, Sohag, Egypt.

*Corresponding Author E-mail:

Accepted 06 April, 2015


This study was carried out to determine the antibacterial activity of Ipomoea reptans extracts which the plant collected from Sudan. All previous literatures and studies carried out but this the first time to study this plant from this area. In this present study, in vitro antibacterial activity of nine Ipomoea reptans extracts were performed to determine the more active fraction against several Gram-positive and Gram-negative bacterial strains. The results exhibited that hexane (IR1), dichloromethane-ethyl acetate (IR6-1, 6-2 and 7), and ethyl acetate fractions are considered more active whereas dichloromethane-ethyl acetate (IR7, 1:1, v/v) showed more activity against the two tested Gram-positive bacteria (Bacillus cereus and Micrococcus ruseus). Consequently, five I. reptans extracts (IR1, IR61, IR62, IR7 and IR8) demonstrated moderately to highly antibacterial activity against the tested Gram-positive bacteria with diameters of inhibition zones ranged from 13 to 17 mm and MIC values ranged from 40 to 120 ppm. Unfortunately, no activity was detected against Gram negative bacteria for all extracts.

Keywords: Ipomoea reptans - Antibacterial activity - Bacillus cereus - Micrococcus ruseus



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