Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
April 2017 Vol. 6(4), pp. 075-078
Copyright © 2017 Global Advanced Research Journals

 

Full Length Research Paper  

A cross sectional study of 1198 cases of thyroid carcinomas in an academic referral center of Pakistan

Arjumand1, Samiyah Tasleem2*, Imran. M.  Baig3, Alfarah Rhematullah4 and Salman Zafar4

1Department of Pathology, Liaquat College of Medicine and Dentistry, Pakistan.
2Department of Microbiology, FUUAST, Karachi Pakistan.
3United Medical and Dental College, Pakistan.
4Hamdard College of Medicine and Dentistry, Karachi Pakistan.

*Corresponding Author E-mail: Samiyahtasleem2005@yahoo.com 

Accepted 11 April, 2017

Abstract

Thyroid cancer is the most common endocrine malignancy which constitutes 92% of all endocrine cancers. There is a lack of population based statistics on thyroid carcinomas in Pakistan but its relative frequency is increasing in our country. To address the need for epidemiological data on thyroid carcinoma in Pakistan, we have evaluated the frequency and types of thyroid carcinoma with respect to age and sex. In a cross-sectional study conducted at Jinnah Postgraduate Medical Center Karachi, We studied the thyroid nodules received in a period of five year, from Jan 2008 to Dec 2012. Pathology slides were studied to determine the morphological type and frequencies of malignant lesion of thyroid. Total of 1198 cases of nodular lesion of thyroid were studied, out of which 99 were malignant. Papillary carcinoma was found to be commonest with a frequency of 89.89% which is followed by follicular and medullary with the same percentage 4.04% and 2.02% hürthle cell carcinoma were found. We observed that the thyroid carcinoma was more prevalent in females 85.86% as compared to males 14.14% with a male to female ratio of 1:6. Thyroid carcinomas were more prevalent in 3rd and 4th decade of life and the mean age for female and male was 32.34 and 35.14 years respectively. Overall thyroid carcinomas are more frequent in females. Papillary carcinoma is the most common morphological type of thyroid carcinomas in both sexes. Thyroid carcinomas are more prevalent in 3rd and 4th decade of life.

Keywords: Thyroid carcinomas, Pakistan


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