Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
May 2015 Vol. 4(5), pp. 248-255
Copyright © 2015 Global Advanced Research Journals

Full Length Research Paper

Assessment of Breast Lesions: A Magnetic Resonance Imaging Study

Marwa Najem Eldin Abdlehamed Mohamed¹, Caroline Edward Ayad^2* Elsafi Ahmed Abdalla²

¹Radiology Department, Dr. Suleiman Alhabib Medical Center-Olaya, Saudi Arabia
²College of Medical Radiological Science, Sudan University of Science and Technology, Khartoum, Sudan

*Corresponding Author E-mail: carolineayad@yahoo.com; Tel: +249183771818; Fax: +249183785215

Accepted 02 May, 2015

Abstract

The purpose of our study was to evaluate the combination of the Diffusion-Weighted Imaging (DWI), Dynamic Contrast Enhancement Magnetic Resonance Imaging (DCE-MRI) and BI-RADS in the improvement of the diagnosis of breast MRI benign and malignant Lesions. This retrospective study included 50 breasts with lesions, their ages were between 26 and 80 years (mean age: 41.78±12.48years). All patients were examined on MRI: T1, T2 weighted images, and underwent consequent biopsy. (DWI) was obtained and (DCE-MRI), BI-RAD were applied and the findings were evaluated .The study took place during the period from June 2012 up to June 2014, at Dr. Suleiman Alhabib Medical Center-Olaya. Findings were 34 benign lesions out of 50 including: breast hematoma, breast cyst, degeneration, fibro-adenoma, fat necrosis, fibrocystic change, myxoid fibroid, papilloma and pseudoangiomatous hyperplasia. Malignant lesions totaled 16 out of 50, including: infiltrating ductal carcinoma, ductal papillary carcinoma and  breast calcification. The average of diameter of the benign lesions was 1.7x1.5cm and that of breast malignant lesions was 2.1x2.0cm. The diagnostic assessment of breast lesions in combination with the assessment of signal intensity and lesion morphologic features, as well as the (DWI), (DCE-MRI), BI-RADS, and dynamic curve assessment with detailed histopathology for each lesion showed significant relationship at P- Value <0.05. Histological results and MRI Findings showed sensitivity of 82%, specificity of 71%, accuracy of 75% and positive predictive value (PPV) of 64%. The additive diffusion-weighted imaging, contrast enhancement MRI, dynamic curves and BIRADS values to T1, T2-weighted MR imaging, for the assessment of breast lesions, would be useful in the analysis of breast MR images. It is likely that all the MR breast imaging combined procedures would be revealed to have an acknowledged task in breast MR imaging without the need of the invasive unnecessary biopsies.

Keywords: BIRAD, Breast, Diffusion-Weighted Imaging, MRI