Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
May 2017 Vol. 6(5), pp. 086-090
Copyright © 2017 Global Advanced Research Journals

Full Length Research Paper  

The relationship between dyspepsia and H. pylori infection in Southern Ethiopia

Misganaw Birhaneselassie* and Abera Alemneh

Hawassa University College of Medicine and Health Sciences

*Corresponding Author E-mail: misganawbs@googlemail.com

Accepted 11 May, 2017 

Abstract

Dyspepsia is a very common problem worldwide. Dyspepsia is a common complaint among Ethiopians. A cross sectional study was conducted in 2010.  In this study 195 subjects, of whom 101 cases and 94 controls were recruited from different areas in southern Ethiopia. All study participants (patients and controls) were interviewed using questions for information on gastro intestinal symptoms, demographic and socio economic status. Whole blood was obtained from all participants. The sera were examined for the presence of IgG antibodies against H. pylori pooled antigens using the Premier EIA method per the manufacturers’ instruction. Data was entered in to the SPSS version 18.0 program and was analyzed for statistical association among variables, considering P=0.05 as statistically significant. Result: Seropositivity for H. pylori was found in 99 (98%) of 101 symptomatic patients and 74 (79%) of 94 asymptomatic participants (OR, 13.39; 95% CI: 3.0 to 59.0). There is a statistical relationship between H. pylori prevalence and age among asymptomatic participants. The prevalence of H. pylori in the study area was very high. Improving the socioeconomic status of the population would reduce the transmission and prevalence of H. pylori, and thus the health status of citizens could be improved.

Keywords: H pylori, dyspepsia, cases and controls