Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
August 2016 Issue Vol. 5(8), pp. 221-227
Copyright © 2016 Global Advanced Research Journals

 

Full Length Research Paper

Antimicrobial activity of nonpolar natural product compounds of Egyptian Ocimum basilicum L

Mohamed H. M. Abd El-Azim*, Amani M. D. El-Mesallamy, Mohamed El-Gerby and Sherin Ali

Department of Chemistry, Faculty of Science, Zagazig University, Egypt.

*Corresponding  Author  E-mail: drmhm1982@gmail.com

Accepted 10 August, 2016

Abstract

In our study; light petroleum ether and diethyl ether extracts of Egyptian Ocimum basilicum L. were analyzed by Gas chromatography-mass spectrometer (GC-MS). Un-saponifiable part of the petroleum ether extract were found to contain twelve compounds with three main constituents were methyl eugenol (87.91%), 4,8,12-Trimethyl-1,3,7,11-tridecatetraene (5.11%) and phytol (3%), and the main constituents of saponifiable fraction of petroleum ether extract contained six fatty acid compounds with two main constituents were α –linoleic methyl ester (65.16 %) and linoleic methyl ester (18.18 %). Also un-saponifiable part of diethyl ether extract were found to contain eight compounds with two main constituents were Cyclopropane,1,1-dimethyl-2-(2,4-pentadienyl) (8.48 %) and 3-Methyl-3-buten-1-ol (5.54%), while saponifiable part gave a traces of free fatty acids. Antimicrobial activities were studied with five bacterial species (Psudomonas aeruginosa, Kelbseilla sp., Salmonella typhi, Staphyllococcus aureus and E. coli, and with five fungal species (Fusarium oxysporum, Aspergillus flavus, Aspergillus niger, Cladosporium sp. and Penicillium sp). Antibacterial activity showed that both extracts have resistance against all bacterial species at 3 mg concentration under investigation. While at 1 mg concentration both extracts have resistance against with Psudomonas aeruginosa, Kelbseilla sp. and E. coli. Also for antifungal activity we found both extracts have resistance against all species 3 mg concentration under investigation. While at 1 mg concentration of both extracts showed no resistance against all species.

Keywords: Antimicrobial activities, GC-MS, Hydrocarbons, Fatty acids and Ocimum basilicum L.

 

Related Articles


Original Research Articles
Omotoso, O. T and Osadiaye, A. L.
The regenerative efficacy of aqueous and methanolic extracts of watermelon, Citrullus lanatus seeds on physiological saline and acetaminophen-induced kidney damage in female albino rats
Glo. Adv. Res. J. Med. Med. Sci. March 2018 Vol: 7(3): - [Abstract] [Full Text - PDF] (8,030 KB)
Nwafor O Emmanuel
Antimicrobial activities of extract of four local spices on bacteria isolated from raw meat sold in Abraka Delta State Nigeria
Glo. Adv. Res. J. Med. Med. Sci. April 2013 Vol: 2(2): - [Abstract] [Full Text - PDF] (351 KB)
Imeh J Okop, Fiokedu S Okorie and Clement O Obadimu
Quantitative evaluation of the spatial distribution and penetration of liquid hydrocarbons in petroleum spilled soil
Glo. Adv. Res. J. Med. Med. Sci. September 2012 Vol: 1(6): - [Abstract] [Full Text - PDF] (1,307 KB)
Adel S Al-Zubairi, Mohamed A Al-Mamary and Eftekhar Al-Ghasani
The Antibacterial, Antifungal, and Antioxidant Activities of Essential Oil from Different Aromatic Plants
Glo. Adv. Res. J. Med. Med. Sci. September 2017 Vol: 6(9): - [Abstract] [Full Text - PDF] (168 KB)
Dauda A. O., Salami, K.O., Oyeyinka, S.A., Esan, O.T., Arise, A.K and Asije A.R.
An Assessment of the Preservative Potentials of Soursop (Annonamuricata) Seed Oil on Plantain and Orange Juice.
Glo. Adv. Res. J. Med. Med. Sci. August 2018 Vol: 7(6): - [Abstract] [Full Text - PDF] (307 KB)
Samuel Omorovie Akporido and Helen Ejiro Kadiri
Effect of Urbanization and Industrialization on Waters of the Benin River- Ethiope River System around Sapele, Nigeria
Glo. Adv. Res. J. Med. Med. Sci. August 2014 Vol: 3(3): - [Abstract] [Full Text - PDF] (1,815 KB)

Current Issue

Viewing Options

View Full Article - PDF
Download Full Article - PDF

Search for Articles

Mohamed HM Abd El-Azim on Google Scholar
Mohamed HM Abd El-Azim on Pubmed
Amani MD El-Mesallamy on Google Scholar
Amani MD El-Mesallamy on Pubmed
Mohamed El-Gerby on Google Scholar
Mohamed El-Gerby on Pubmed
Sherin Ali on Google Scholar
Sherin Ali on Pubmed

Statistics

Viewed 1402
Printed 363
Downloaded 1138
Powered By iPortal Works