Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
July 2017 Vol. 6(8), pp. 175-178
Copyright © 2017 Global Advanced Research Journals


Case Report 

Report of Refeeding Syndrome in Chronic Obstructive Pulmonary Disease Elderly Patient

Fernando Roccia1*, Luca Gallelli2*, Benedetta Campolo1, Giuseppina Marrazzo1, Mariarita Perri3, Claudia Roccia2, Girolamo Pelaia1, Rosario Maselli1 and Erika Cione3§ 

1Department of Medical and Surgical Science, School of Medicine, University of Catanzaro, Italy.
2Department of Health Science, School of Medicine, University of Catanzaro, Clinical Pharmacology and Pharmacovigilance Unit, Mater Domini University Hospital, Catanzaro, Italy.
3Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Italy

*Roccia and Gallelli share the authorship
§Corresponding Author E-mail:; Phone: +390984493193

Accepted 29 August, 2017


Refeeding Syndrome (RS) is a life-threatening condition where the body is predisposed to a non-obvious multi-deficiency occurring with minerals shifts between the intra- and extracellular compartments. We used biochemical parameters and Naranjo probability scale. Herein we report the development of RS in a patient with chronic obstructive pulmonary disease, treated with parenteral nutrition (PN). In our patient cholesteric index (with an increase of gamma-GT and bilirubin) was observed, as well as the association between PN and clinical symptoms (Naranjo score 7). PN was stopped, replaced with nasogastric feeding at first and subsequently to a percutaneous endoscopic gastrostomy tube, with a time-related improvement of symptoms. Although PN represents an effective approach in patients that cannot be treated with enteral nutrition its use in elderly patient can be related to the development of adverse metabolic reactions.

Keywords: Refeeding Syndrome, elderly, parenteral nutrition.



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