Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
September 2012 Vol. 1(8), pp. 203-207
Copyright © 2012 Global Advanced Research Journals


Full Length Research Paper

White blood cells` response of female wistar rats following induced physical and oxidative stress

A.I. Shugaba1*, S. A. Ojo2, A.S. Asala3, A.M. Rabiu4, C.B. Uzokwe1 and J.O. Hambolu2

1Department of anatomy, faculty of medical sciences, university of Jos, Nigeria.
2Department of vetinary anatomy, faculty of vetinary medicine, A.B.U. Zaria, Nigeria.
3Department of anatomy, college of health sciences, university of Abuja, Nigeria.
4Department of physiology, faculty of medical sciences, university of Jos, Nigeria.

*Corresponding author E-mail:

Accepted 16 August, 2012


The effect of induced physical and oxidative stress on the white blood cells (WBC) of female Wistar rats was investigated. 40 matured female Wistar rats were divided into four groups (A.B.C.D) ten per group. Group A, control, Group B, mono enucleation, Group C, bilateral enucleation and Group D, alcohol treated. The total and differential white cell counts were evaluated over the six weeks period of the induced stress. The results revealed no difference in the average total and differential white cell counts of the mono and bilaterally enucleated groups. While the alcohol treated group showed increase especially in the total WBC, neutrophils and eosinophils compared to the control group (P-value <0.05).

Keywords: Induced stress, Female Wistar rats, White blood cells (WBC).


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