Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
October 2015 Vol. 4(10), pp. 449-454
Copyright © 2015 Global Advanced Research Journals

Full Length Research Paper

Changes in Lipids Profile and Insulin Level in Obese Sudanese Women

Omer Mohamed Shoaib¹*, Ihab Hamed Nourein², Abuobieda Balla Abusharib³ and Moawia Ahmed Elbadri⁴

¹Assistant Professor - Departmentof Clinical Chemistry, Faculty of Medical Laboratory Sciences, Alzaeim Alazhari University- Sudan.
²Department of Pathology, Collage Medicine, Najran University, KSA.
³Department of Pathology, Collage Medicine, Najran University, KSA.
⁴Department of Microbiology, Collage of Medicine, Najran University, KSA.

*Corresponding Author E-mail: oshoaib13@yahoo.com Contact No.:+966559791836

Accepted 28 October 2015 

Abstract

As obesity is rapidly becoming a major medical issue, it’s associated with many cardiovascular risk factors and others public health problem, the aim of our present study is to investigate the concentration and evaluate potential role of insulin and lipids profile, total cholesterol (TC), Triglyceride (Trig), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein- cholesterol (LDL-C) levels and insulin among obese Sudanese women. A prospective analytic, cross- sectional and hospital-based study included Sudanese women from Khartoum- State- Sudan, in period from March 2012 to May 2014. A total of 200 obese Sudanese women were compared with 100 healthy non obese women as control group, all of them were age-matched, Samples were taken after overnight fasting then serum insulin and lipids were analyzed using ELISA technique and colorimetric methods. The (mean ± SD) of serum insulin and (TC, Trig, HDL-C and LDL-C) in obese women were 11.06±6.21µIU/ml,166.95±46.94mg/dl, 89.89±33.36 mg/dl, 43.83±2075mg/dl, 104.55±52.29mg/dl respectively, while that of control group, the (mean ± SD) of serum insulin, TC, Trig, HDL-C and LDL-C were 4.52±1.60µIU/ml, 145.14±31.19mg/dl,  82.13±26.51mg/dl, 51.02±1481mg/dl, 72.62±30.04 mg/dl, respectively. Serum insulin, TC, Trig, LDL-Care significant elevated while HDL-Cis decreased in obese as compared with control group (P<0.05). Patients with obesity have significant increased levels of Serum insulin, TC, Trig, LDL-C and HDL-C is decreased in obese Sudanese women.

Keywords: Obesity, Total cholesterol, Triglyceride, HDL-C, LDL-C, Sudanese.