Global Advanced Research Journal of Microbiology (GARJM) ISSN: 2315-5116
November 2020 Vol. 9(5): pp. 069-072
Copyright © 2020 Global Advanced Research Journals

 

Full Length Research Paper

 

Epidemiology of Pseudomonas aeruginosa and Its Resistance in Cameroon: Systematic Review and Meta-Analysis

Yves Le Grand Napa Tchuedji1, Hortense Gonsu Kamga2,3, Emilia Lyonga Mbamyah2,Anicette Chafa Betbeui3,Francois-Xavier Etoa1and Yap BoumII4,5

 

1Department of Microbiology, Laboratory of Microbiology, University of Yaoundé I, Yaoundé, Cameroon.

2Department of Microbiology, Parasitology, Haematology and InfectiousDiseases, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaoundé, Cameroon

3Laboratory of Bacteriology, UniversityTeachingHospital, Yaounde, Cameroon.

4Epicenter Africa Research Centre, Yaoundé, Cameroon

Email: tchuedji@yahoo.fr

Accepted 10 November, 2020

 

Abstract

Background: Pseudomonas aeruginosa is a non-fermentative bacteria which present a rapid increase in the rates of infections across the world. Pseudomonas aeruginosa ranks third among the resistant bacteria responsible for nosocomial infections. Aim: To assess the distribution and evolution of resistance of Pseudomonas aeruginosa in Cameroon. Methods: We carried out a systematic review of the research publications that determined the resistance phenotypes of Pseudomonas aeruginosa in Cameroon. A meta-analysis of the data was carried out to synthesize the data on resistance phenotypes, their distribution and their evolution in Cameroon. Results: A considerable increase in resistance to ceftazidime, aztreonam, gentamycin and tobramycin between 2005 and 2011 was observed. In addition, an increase in resistance to imipenem was noted between 2011 and 2013. The city of Douala has a high frequency of Pseudomonas aeruginosa followed by Buea and Yaounde. Conclusion: Pseudomonas aeruginosa has a high frequency and resistance to several antibiotics in Cameroon. There is a need to continue surveillance in several hospitals and in several regions of Cameroon in order to implement policies and measures to fight infections and antibiotic resistance.

Keywords: Pseudomonas aeruginosa, resistance, antibiotics, epidemiology, clinical isolates..

 

 

 

Background: Pseudomonas aeruginosa is a non-fermentative bacteria which present a rapid increase in the rates of infections across the world. Pseudomonas aeruginosa ranks third among the resistant bacteria responsible for nosocomial infections. Aim: To assess the distribution and evolution of resistance of Pseudomonas aeruginosa in Cameroon. Methods: We carried out a systematic review of the research publications that determined the resistance phenotypes of Pseudomonas aeruginosa in Cameroon. A meta-analysis of the data was carried out to synthesize the data on resistance phenotypes, their distribution and their evolution in Cameroon. Results: A considerable increase in resistance to ceftazidime, aztreonam, gentamycin and tobramycin between 2005 and 2011 was observed. In addition, an increase in resistance to imipenem was noted between 2011 and 2013. The city of Douala has a high frequency of Pseudomonas aeruginosa followed by Buea and Yaounde. Conclusion: Pseudomonas aeruginosa has a high frequency and resistance to several antibiotics in Cameroon. There is a need to continue surveillance in several hospitals and in several regions of Cameroon in order to implement policies and measures to fight infections and antibiotic resistance. 

Related Articles


Original Research Articles
Alexandra Lacatusu, Ioana Iordan, Carmen Manciuc
Clostridium difficile infection- an overview on recurrences over two years
Glo. Adv. Res. J. Microbiol April 2019 Vol: 8(3): - [Abstract] [Full Text - PDF] (533 KB)
Njock TE and Sama V
Quantification and correlation of African cassava mosaic disease parameters on cassava genotypes (Manihot esculenta, Crantz) in Buea, Cameroon.
Glo. Adv. Res. J. Microbiol April 2015 Vol: 4(4): - [Abstract] [Full Text - PDF] (189 KB)
Javad Nourian, Fatemeh Mehravar and Mohammad Bagher Sohrabi
Comparison of the cost-effectiveness of Propofol intravenous anesthesia and Isoflurane inhalation anesthesia: a randomized clinical Trial
Glo. Adv. Res. J. Microbiol June 2017 Vol: 6(6): - [Abstract] [Full Text - PDF] (98 KB)
Rajech Sharkia, Muhammad Mahajnah, Ahmad Sheikh-Muhammad, Mohammad Khatib and Abdelnaser Zalan
Trends in the prevalence of type 2 diabetes mellitus among Arabs in Israel: A community health survey
Glo. Adv. Res. J. Microbiol April 2018 Vol: 7(4): - [Abstract] [Full Text - PDF] (139 KB)
Durugbo Ernest Uzodimma
Medico-Ethnobotanical inventory of Ogii, Okigwe Imo State, South Eastern Nigeria - I
Glo. Adv. Res. J. Microbiol November 2013 Vol: 2(2): - [Abstract] [Full Text - PDF] (237 KB)
Ahmed Ibrahim Hashim, Amal Mubarak Hassan Mubarak, Nosiba Ahmed Hassan Hamed, and Ahmed Bakheet Abd Alla
Isolation of Aerobic Bacteria from Wounds of Diabetic Patients Undergoing Hyperbaric Oxygen Therapy in Khartoum State
Glo. Adv. Res. J. Microbiol June 2018 Vol: 7(4): - [Abstract] [Full Text - PDF] (188 KB)

Current Issue

Viewing Options

View Full Article - PDF
Download Full Article - PDF

Search for Articles

Yves Le Gr on Google Scholar
Yves Le Gr on Pubmed
Napa Tchuedji on Google Scholar
Napa Tchuedji on Pubmed
Hortense Gonsu Kamga on Google Scholar
Hortense Gonsu Kamga on Pubmed
Emilia Lyonga Mbamyah on Google Scholar
Emilia Lyonga Mbamyah on Pubmed
Anicette Chafa Betbeui on Google Scholar
Anicette Chafa Betbeui on Pubmed
Francois-Xavier Etoa on Google Scholar
Francois-Xavier Etoa on Pubmed
Yap BoumII on Google Scholar
Yap BoumII on Pubmed

Statistics

Viewed 1285
Printed 51
Downloaded 328
Powered By iPortal Works