Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
September 2013 Vol. 2(9), pp. 193-198
Copyright © 2013 Global Advanced Research Journals
Full Length Research Paper
Kaposi Sarcoma: A review of 387 cases seen in Yaounde, Cameroon
Enow Orock GE1*, Verla VS2, Ashuntantang GE3, Ndom P4, and Doh AS4
1Yaounde Cancer Registry, Department of Pathology, General Hospital, Yaounde, Cameroon.
2Department of Internal Medicine , University of Buea, Cameroon.
3Department of Internal Medicine, General Hospital, Yaounde, Cameroon.
4National Cancer Control Committee, Yaounde, Cameroon.
*Corresponding Author E-mail: email@example.com; Tel: 237 77716045
Accepted 08 September, 2013
The introduction of highly active antiretroviral therapy has improved on survival and increased the life expectancy of HIV/AIDS patients. This increase predisposes to a high incidence of HIV-associated malignancies among these patients. Kaposi sarcoma is one of the commonest AIDS-related malignancy in our community and is sometimes the clinical presentation that heralds the infection. We were interested to find out the epidemiological and anatomo-clinical aspects of the disease in this population. Data of the Yaounde Population Cancer Registry on patients diagnosed with Kaposi sarcoma between 2004 and 2011 was reviewed in this retrospective population study. Epidemiological and anatomo-clinical data of the patient and the tumour were analyzed. Chi-squared tests were used for statistical analysis. 387 patients with Kaposi sarcoma, including 64% males and 37% females were found in 8 years, giving an annual average of 48. About 55% of the disease was AIDS-associated. The age range for patients was 1-86 years at an average of 42.01 years and median of 40 years. The male average age was 42.4 years and 36.1 years for females. In males the disease is significantly more located in the skin, while the digestive tract with exception of the stomach is a significantly more topographic site for the tumour in females. 3 patients were HIV negative. There is no difference among the sexes for location of the tumour in the stomach, lymph nodes and lung. Kaposi sarcoma is common our community, mostly affects males at mid age, and is predominantly AIDS-related. The tumour location is sex-dependent at certain sites. HIV negative persons are not immune to the disease. HIV serology is recommended for all patients who present with a Kaposi sarcoma and concomitantly, all HIV seropositive patients should be screened for the disease.
Keywords: Kaposi, sarcoma, AIDS, Yaounde.
- View Full Article - PDF
- Download Full Article - PDF
- Enow Orock GE on Google Scholar
- Enow Orock GE on Pubmed
- Verla VS on Google Scholar
- Verla VS on Pubmed
- Ashuntantang GE on Google Scholar
- Ashuntantang GE on Pubmed
- Ndom P on Google Scholar
- Ndom P on Pubmed
- on Google Scholar
- on Pubmed
- Doh AS on Google Scholar
- Doh AS on Pubmed
Search for Articles
- Viewed 3578
- Printed 735
- Downloaded 1572